Details

Activation of Viruses by Host Proteases


Activation of Viruses by Host Proteases



von: Eva Böttcher-Friebertshäuser, Wolfgang Garten, Hans Dieter Klenk

178,49 €

Verlag: Springer
Format: PDF
Veröffentl.: 22.05.2018
ISBN/EAN: 9783319754741
Sprache: englisch

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Beschreibungen

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
Introduction.- Viruses.- Influenzaviruses.- Paramyxo-, Hendra-, Nipahviruses.- Coronaviruses.- Flaviviruses.- Arenaviruses.- Filoviruses.- Proteases.- Proproteinconvertases.- Serinproteases.- Transmembrane serinproteases.- Cathepsins.- Protease inhibitors.
Eva Böttcher-Friebertshäuser, Wolfgang Garten, and Hans Dieter Klenk are at the Institute of Virology, Philipps University Marburg, 35043 Marburg, Germany
This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
Presents recent findings on this topicDeals with all aspects of the role of proteases in virus activationExplores the topic from different points of view

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